KRAS, KRAS proto-oncogene, GTPase, 3845

N. diseases: 1213; N. variants: 54
Source: ALL
Variant DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Disease Class Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs8720
rs8720 		1.000 0.080 12 25206009 3 prime UTR variant T/C snv 0.49
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		Digestive System Diseases; Neoplasms 0.010 1.000 1 2020 2020
dbSNP: rs1137188
rs1137188 		1.000 0.080 12 25206418 3 prime UTR variant G/A snv 0.49
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		Digestive System Diseases; Neoplasms 0.010 1.000 1 2017 2017
dbSNP: rs1137188
rs1137188 		1.000 0.080 12 25206418 3 prime UTR variant G/A snv 0.49
CUI: C0027651
Disease: Neoplasms
Neoplasms 		Neoplasms 0.010 1.000 1 2017 2017
dbSNP: rs12587
rs12587 		0.827 0.200 12 25205894 3 prime UTR variant T/G snv 0.49
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma 		Neoplasms; Nervous System Diseases 0.010 1.000 1 2019 2019
dbSNP: rs12587
rs12587 		0.827 0.200 12 25205894 3 prime UTR variant T/G snv 0.49
CUI: C0027708
Disease: Nephroblastoma
Nephroblastoma 		Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases 0.010 1.000 1 2019 2019
dbSNP: rs12587
rs12587 		0.827 0.200 12 25205894 3 prime UTR variant T/G snv 0.49
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma 		Neoplasms 0.010 1.000 1 2019 2019
dbSNP: rs12587
rs12587 		0.827 0.200 12 25205894 3 prime UTR variant T/G snv 0.49
CUI: C1333015
Disease: Childhood Kidney Wilms Tumor
Childhood Kidney Wilms Tumor 		Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases 0.010 1.000 1 2019 2019
dbSNP: rs12587
rs12587 		0.827 0.200 12 25205894 3 prime UTR variant T/G snv 0.49
CUI: C4086165
Disease: Childhood Neuroblastoma
Childhood Neuroblastoma 		Neoplasms 0.010 1.000 1 2019 2019
dbSNP: rs57698689
rs57698689 		1.000 0.080 12 25205729 3 prime UTR variant TT/-;T delins 0.48
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion 		0.010 1.000 1 2017 2017
dbSNP: rs57698689
rs57698689 		1.000 0.080 12 25205729 3 prime UTR variant TT/-;T delins 0.48
CUI: C0686619
Disease: Secondary malignant neoplasm of lymph node
Secondary malignant neoplasm of lymph node 		Pathological Conditions, Signs and Symptoms; Neoplasms 0.010 1.000 1 2017 2017
dbSNP: rs712
rs712 		0.677 0.360 12 25209618 3 prime UTR variant A/C snv 0.46
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis 		Pathological Conditions, Signs and Symptoms; Neoplasms 0.040 1.000 4 2014 2019
dbSNP: rs712
rs712 		0.677 0.360 12 25209618 3 prime UTR variant A/C snv 0.46
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		Neoplasms 0.040 1.000 4 2015 2019
dbSNP: rs712
rs712 		0.677 0.360 12 25209618 3 prime UTR variant A/C snv 0.46
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		Neoplasms 0.040 1.000 4 2015 2019
dbSNP: rs712
rs712 		0.677 0.360 12 25209618 3 prime UTR variant A/C snv 0.46
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		Digestive System Diseases; Neoplasms 0.030 1.000 3 2014 2019
dbSNP: rs712
rs712 		0.677 0.360 12 25209618 3 prime UTR variant A/C snv 0.46
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.020 1.000 2 2014 2019
dbSNP: rs712
rs712 		0.677 0.360 12 25209618 3 prime UTR variant A/C snv 0.46
CUI: C0279671
Disease: Cervical Squamous Cell Carcinoma
Cervical Squamous Cell Carcinoma 		Neoplasms; Female Urogenital Diseases and Pregnancy Complications 0.010 1.000 1 2015 2015
dbSNP: rs712
rs712 		0.677 0.360 12 25209618 3 prime UTR variant A/C snv 0.46
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		Neoplasms; Respiratory Tract Diseases 0.010 1.000 1 2015 2015
dbSNP: rs712
rs712 		0.677 0.360 12 25209618 3 prime UTR variant A/C snv 0.46
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		Neoplasms; Respiratory Tract Diseases 0.010 1.000 1 2015 2015
dbSNP: rs712
rs712 		0.677 0.360 12 25209618 3 prime UTR variant A/C snv 0.46
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		Digestive System Diseases; Neoplasms 0.010 1.000 1 2017 2017
dbSNP: rs712
rs712 		0.677 0.360 12 25209618 3 prime UTR variant A/C snv 0.46
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma 		Neoplasms; Endocrine System Diseases 0.010 1.000 1 2014 2014
dbSNP: rs712
rs712 		0.677 0.360 12 25209618 3 prime UTR variant A/C snv 0.46
CUI: C0279626
Disease: Squamous cell carcinoma of esophagus
Squamous cell carcinoma of esophagus 		Digestive System Diseases; Neoplasms 0.010 1.000 1 2020 2020
dbSNP: rs712
rs712 		0.677 0.360 12 25209618 3 prime UTR variant A/C snv 0.46
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		Neoplasms; Skin and Connective Tissue Diseases 0.010 1.000 1 2015 2015
dbSNP: rs712
rs712 		0.677 0.360 12 25209618 3 prime UTR variant A/C snv 0.46
CUI: C0040137
Disease: Thyroid Nodule
Thyroid Nodule 		Neoplasms; Endocrine System Diseases 0.010 1.000 1 2019 2019
dbSNP: rs712
rs712 		0.677 0.360 12 25209618 3 prime UTR variant A/C snv 0.46
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X 		Nutritional and Metabolic Diseases 0.010 1.000 1 2015 2015
dbSNP: rs712
rs712 		0.677 0.360 12 25209618 3 prime UTR variant A/C snv 0.46
CUI: C0751075
Disease: Cancer of Digestive System
Cancer of Digestive System 		Digestive System Diseases; Neoplasms 0.010 1.000 1 2017 2017